Bioinformatics Mcqs

Page No. 79

Conservation of gene order due to operon structure is _______ so interactions of proteins specific to eukaryotes cannot be detected by method of Conservation of gene order.


anot applicable to archea genomes

✖


bnot applicable to prokaryote genomes

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c applicable to eukaryote genomes

✖


dnot applicable to eukaryote genomes

✓



In a quantitative assessment of this method (Conservation of gene order) using the genome of the parasitic organism Mycoplasma genitalium as a benchmark.


a True

✓


bFalse

✖


ceither true and false

✖


dnone of the mentioned

✖


View Answer True

Members of a stable complex are often co-regulated and thus will be detected by the method of Conservation of gene order.


aTrue

✓


bFalse

✖


ceither true and false

✖


dnone of the mentioned

✖


View Answer True

When comparing pairs of genes or sets of genes in different genomes for this purpose, it is not mandatory for the genes to be orthologs.


aTrue

✖


bFalse

✓


ceither true and false

✖


dnone of the mentioned

✖


View Answer False

Genes that are consistently part of the same operon across different, distantly related genomes are likely to be part of the same protein complex or functional process across all species.


aTrue

✓


bFalse

✖


ceihter true and false

✖


dnone of the mentioned

✖


View Answer True

Interactions between proteins can be predicted computationally by looking for sets of genes that occur as a _______


asingle gene in at least one genome

✓


bmultiple genes in at least one genome

✖


cmultiple genes in various genomes

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d single gene in various genomes

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Experimentation is most desirable over computational methods by every means.


aTrue

✖


bFalse

✓


ceihter ture and false

✖


dnone of the mentioned

✖


View Answer False

Which of the following is untrue about Shotgun Sequencing?


aWhen DNA fragments derived from different chromosomal regions have repeats of the same sequence, they will appear to overlap

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bWhen DNA fragments derived from different chromosomal regions have repeats of the same sequence, they will appear to scrutinize

✓


c In a new whole shotgun approach, Celera Genomics is sequencing both ends of DNA fragments of short (2 kb), medium (10 kb), and long (BAC or >100 kb) lengths

✖


dA large number of reads are then assembled by computer

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An alternative method is to sequence all the subclones, produce a computer database of the sequences, and then have the computer assemble the sequences from the overlaps that are found.


aTrue

✓


bFalse

✖


ceither true and false

✖


dnone of the mentioned

✖


View Answer True

Once the correct map has been obtained, unique overlapping clones are chosen for sequencing.


aTrue

✓


bFalse

✖


ceither true and false

✖


dnone of the mentioned

✖


View Answer True

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