Bioinformatics Mcqs

Page No. 81

The translated sequence can then be compared to a database of protein sequences with the hope of finding a strong similarity to a protein of known function, and hence to identify the function of the cloned EST.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

An important development for computational purposes was the decision by Craig Venter to prepare databases of partial sequences of the expressed genes, called expressed sequence tags or ESTs.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

Using cDNA sequence with the __________ it is much simpler to locate protein-encoding sequences in these molecules.


aexons taken out


bexons removed


cintrons added


dintrons removed


View Answer introns removed

cDNA libraries have been prepared that have the same sequences as the mRNA molecules produced by organisms, or else cDNA copies are sequenced directly by RT-PCR (copying of mRNA by reverse transcriptase followed by sequencing of the cDNA copy by the polymerase chain reaction).


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

Two common goals in sequence analysis are to identify sequences that encode proteins, which determine all cellular metabolisms, and to discover sequences that regulate the expression of genes or other cellular processes.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

For computer analysis of proteins, it is more convenient to use single-letter than three letter amino acid codes.


aTrue


bFalse


ceither ture of false


dnone of these


View Answer True

According to standard amino acid code letters which of the given pair is not right?


aK- lysine


bY- tyrosine


cQ- glutamine


d R- serine


View Answer R- serine

Which of the given statements is untrue?


aSequence and other data files that contain non-ASCII characters also may not be transferred correctly from one machine to another and may cause unpredictable behavior of the communications software


b The ASCII mode is useful for transferring text files, and the binary mode is useful for transferring compressed data files, which also contain non-ASCII characters


cASCII and binary modes cannot be set by the user


dMost sequence analysis programs also require not only that a DNA or protein sequence file be a standard ASCII file, but also that the file be in a particular format such as the FASTA format



Which of the given statements is incorrect about ASCII and Hexadecimal?


a Computers store sequence information as simple rows of sequence characters called strings, which are similar to the sequences shown on the computer terminal


bEach character is stored in binary code in the smallest unit of memory, called a byte


cEach character is stored in binary code in the smallest unit of memory, called a bit


dBy convention, many of these combinations have a specific definition, called their ASCII equivalent



Which of the following is wrong about Abstract Syntax Notation Sequence Format?


aThe information is much more difficult to read by eye than a GenBank formatted sequence


bAbstract Syntax Notation (ASN.1) is a formal data description language that has been developed by the computer industry


cAll the information found in other forms of sequence storage, e.g., the GenBank format, is present. For example, sequences can be retrieved in this format by ENTREZ


dTaxonomic information and bibliographic information cannot be encoded with this format



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