Bioinformatics Mcqs

Page No. 2

What does this representation mean- R.L.[EQD]?


aAn arginine- Amino acid- Leucine- Amino acid- Either Apartic acid, glutamic acid or glutamine


b An arginine- Leucine- Either Apartic acid, glutamic acid or glutamine


cAn arginine- Leucine- Amino acid- Either Apartic acid, glutamic acid or glutamine


dAn arginine- Leucine- Apartic acid and glutamic acid and glutamine



.Which of the following is not a characteristic of exact matches in regular expression?


aThere must be a strict match of sequence patterns


bAny variations in the query sequence from the predefined patterns are not allowed


cProvide more permissive matching by allowing more flexible matching of residues of similar biochemical properties


dSearching a motif database using this approach results in either a match or non-match



Which of the following is not a characteristic of Fuzzy or approximate matches in regular expression?


a This method is able to include more variant forms of a motif with a conserved function


bthe rule of matching is based on observations, not actual assumptions


c with the more relaxed matching, there is increase of the noise level and false positives


d the rule of matching is based on assumptions not actual observati



While analysing motif sequences, what is the major disadvantageous feature of PROSITE?


aThe database constructs profiles to complement some of the sequence patterns


bThe functional information of these patterns is primarily based on published literature


cSome of the sequence patterns are too short to be specific


dLack of specificity about probability and variation and relation between them



Emotif uses which databases for alignment of sequences? a) BLOCKS and PRINTS databases


aBLOCKS and PRINTS databases


bPROSITE


cPROSITE


dPRINTS



In terminologies related to regular expressions which of the following is false about terms and operators?


aTerms are strings or substring


bOperators combine terms and expressions


cOperators do not have precedence


dOperators have precedence like arithmetic operators



In regular expressions, which of the following pair of pattern is wrongly matched with its significance?


a[ ] – Or


b{ } – Not


c ( ) – Repeats


d Z – Any


View Answer Z – Any

Which of the following best defines regular expressions?


aThey are made up of terms, operators and modifiers


b They describe string or set of strings to find matching patterns


c They are strictly restricted to alignment and corresponding score


dThey consist of set of rules for the connotations of various amino acid residues



While scanning for similarities in motifs, how regular expressions’ techniques work?


aIt represents a sequence family by a string of characters and further compares them


b An algorithm similar to dynamic programming is used


c Dot matrix analysis is used in this type of sequence analysis


d Matrix analysis methods are used in this type



Point out the wrong or irrelevant mathematical method in motif analysis.


aEnumeration


bProbabilistic Optimization


c Deterministic Optimization


d Literature mining


View Answer Literature mining

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