Bioinformatics Mcqs

Page No. 7

A multiple sequence alignment or a motif is often represented by a graphic representation called a ______


alogo


bmotto


calgorithm


dalgo


View Answer logo

Gibbs is a web-based program that uses the Gibbs sampling approach to look for _____ gap-free segments for either DNA or protein sequences.


ashort, partially conserved


b long, partially conserved


clong, conserved


d short, not conserved



In the web-based program MEME, the computation is a _____ step procedure.


aone


btwo


cthree


dfour


View Answer two

MEME stands for _____________


aMultiple Expectation Maximization for Motif Elicitation


bMultiple Expectation Maximization for Motif Extraction


cMega Expectation Maximization for Motif Elicitation


d Micro Expectation Maximization for Motif Extraction



Which of the following is true about Expectation Maximization (EM) method?


aThe log odds scores of the PSSM are modified at the end of the process


bThe procedure stops prematurely if the scores reach convergence


cThe final result is not sensitive to the initial alignment


dLocal optimum is an advantage of EM method



Which of the following is untrue about Expectation Maximization (EM) method?


a It is used to find hidden motifs


bThe method works by first making a random or guessed alignment of the sequences to generate a trial PSSM


cThe trial PSSM is used to compare with each sequence individually


dThe log odds scores of The log odds scores of the PSSM are modified at the end of the processPSSM are modified at the end of the process



For what type of sequences Gibbs sampling is used?


aClosely related sequences


bDistinctly related sequences


cDistinctly related sequences that share common motifs


dClosely related sequences that share common motifs



Dot plot of repeating elements would be small crosses on plot.


aTrue


bFalse


ceither true and false


dnone of these


View Answer False

Vertical frame shifts show ______ while the horizontal ones show _______


ainsertion, insertion


binsertion, deletion


cdeletion, deletion


ddeletion, insertion


View Answer insertion, deletion

Isolated dots that are not on the diagonal represent exact matches.


aTrue


b False


ceither true and false


dnone of these


View Answer False

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