Bioinformatics Mcqs

Page No. 77

Sets of proteins that are part of stable complexes and sets of proteins involved in transient interactions ____ in terms of the similarity in gene expression among the set of proteins.


aare similar


bdiffer


care same


dshow similar function


View Answer differ

Stable complexes consist of proteins that are _____ associated with each other, like many ____ proteins for instance.


atemporarily, oligomeric


bemporarily, monomeric


cpermanently, oligomeric


dermanently, monomeric



There exist three types of interactions between domains. Which of the following is not one of them?


aStable complex


bTransient interaction


cMulti-domain protein


dUnstable interaction


View Answer Unstable interaction

The physical contacts between domains are crucial for the functioning of the cellular machinery.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

Across the different types of catalytic families, the position of the two domains with respect to one another varied, but only within a range of about ______


a20°


b10°


c90°


d80°


View Answer 90°

The linkers between the catalytic domain and the Rossmann domain were conserved in each family.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

The investigation (Aloy and Russel) of domain combinations in multidomain proteins by Bashton and Chothia focuses on two-domain proteins belonging to the Rossmann domain family.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

In order to understand the geometry of domain combinations, different structures of homologous pairs of domains must be studied.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

Almost ______ engage in interactions with domains from their own family when one includes


aone fifith of all known families


bone fourth of all known families


call of all known families


dhalf of all known families



Most domain families only interact with one or two other families, while a few families are extremely versatile in their interactions and are connected to many families.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

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