Bioinformatics Mcqs

Page No. 46

Physical maps are constructed by using a chromosome walking technique.


aTrue


bFalse


ceither true and fasle


dnone of the mentioned


View Answer True

Physical maps are maps of locations of identifiable landmarks on a genomic DNA _______ inheritance patterns.


aremotely related to


brelated to


c regardless of


dassociated with


View Answer regardless of

One centiMorgan is defined as _________ percentage of the total recombination events.


aone


bten


c0.1


d0.01


View Answer one

Genetic linkage maps, also called genetic maps, identify the relative positions of genetic markers on a chromosome and are based on how frequent the markers are inherited together.


aTrue


b False


ceither true and false


dnone of the mentioned


View Answer True

Genetic markers are ______ portions of a _______ whose inheritance patterns can be followed.


aunidentifiable, genes


bunidentifiable, chromosome


cidentifiable, chromosome


didentifiable, genes



Which of the following is untrue about the genome mapping?


a It doesn’t lead to the understanding of a genome structure


b It involves identifying relative locations of genes


cIt involves identifying traits


dIt involves identifying mutations



The whole genome shotgun approach can produce a draft sequence very rapidly because it is based on the direct sequencing approach.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

The hierarchical approach is ____ and _____ than the shotgun approach because it involves an initial clone-based physical mapping step.


aslower, less costly


bfaster, more costly


cfaster, less costly


dslower, more costly


View Answer slower, more costly

In hierarchical genome sequencing approach, based on the results of _______ mapping _______of the BAC clones on a chromosome can be determined.


aphysical, the locations and orders


bphysical, only the locations


c cytological, only the locations


dphysical, only the orders



The hierarchical genome sequencing approach is ______


aentirely dissimilar to the shotgun approach


bdissimilar to the shotgun approach


csimilar to the shotgun approach, but on a larger scale


dsimilar to the shotgun approach, but on a smaller scale



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