Bioinformatics Mcqs

Page No. 45

Which of the following is untrue regarding RNA structure?


aRNA structure 4.6 is a Windows implementation of the Zuker algorithm


bIt includes additional options for other folding algorithms and incorporation of experimental data


cThe authors of RNA structure collaborate very closely with the Turner laboratory and keep the most up-to-date thermodynamic parameters


dThe OligoWalk program cannot be used for siRNA design



The probability model mentioned above was a hybrid combination of HMMs and SCFGs trained on sno RNAs.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

The probabilistic model was used to identify small nucleolar (sno) RNAs in the yeast genome that methylate ribosomal RNA.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

Fichant and Burks (1991) described a program, tRNAscan, that searches a genomic sequence with a sliding window searching simultaneously for matches to a set of invariant bases and conserved self-complementary regions in tRNAs with an accuracy of 97.5%.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

One of the first methods used to find tRNA genes was to search for sequences that are complementary and can fold into a knot like the three found in tRNAs.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer False

_____ molecules can simply be identified based on their sequence similarity with already-known sequences.


aLarger, less conserved


bLarger, highly conserved


csmaller, highly conserved


dshorter, highly conserved



One of the fundamental events that occur in meiosis is crossing over in which homologous chromosomes exchange segments causing a reshuffling of genes.


aTrue


bFalse


ceither ture and false


dnone of the mentioned


View Answer True

In medical applications, the ultimate goal of gene mapping is to disease genes.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

Cytologic maps can be considered to be of _____ resolution and hence somewhat ______ physical maps.


avery high, inaccurate


bvery low, accurate


cvery high, accurate


dvery low, inaccurate


View Answer very low, inaccurate

Which of the following is untrue about cytologic maps?


aThey cannot be directly observed under microscope


bThey refer to banding patterns


cThey can be viewed on stained chromosomes


dThey can be directly observed under microscope



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