Bioinformatics Mcqs

Page No. 24

The final step involves pairwise alignment by extending from the words in both directions while counting the alignment score using the same substitution matrix.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

In sequence alignment by BLAST, the second step is to search a sequence database for the occurrence of these words.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

In sequence alignment by BLAST, each word from query sequence is typically _______ residues for protein sequences and _______ residues for DNA sequences.


aten, eleven


b three, three


c three, eleven


dthree, ten


View Answer three, eleven

.The BLAST program was developed in _______


a1992


b1995


c1990


d1991


View Answer 1990

Z-score describes the number of standard deviations from the mean score for the database search.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

FASTA doesn’t use bit scores.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer False

FASTX, which compares a protein query sequence to a translated DNA database.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer False

The web-based FASTA program is offered by the European Bioinformatics Institute.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

The last step is to perform a statistical evaluation of the final alignment as in BLAST, which produces the E-value.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

In FASTA, neighboring high-scoring segments along the same diagonal are selected and joined to form a single alignment.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

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