Bioinformatics Mcqs

Page No. 23

Sensitivity refers to the ability to find as many correct hits as possible.


aTrue

✓


bFalse

✖


ceither true and false

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dnone of the mentioned

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View Answer True

Which of the following is not one of the requirements for implementing algorithms for sequence database searching?


aSize of the dataset

✓


bSensitivity

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cSpecificity

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dSpeed

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View Answer Size of the dataset

Dynamic programming method is the fastest and most practical method.


aTrue

✖


bFalse

✓


ceither true and false

✖


dnone of the mentioned

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View Answer False

The main application of pairwise alignment is retrieving biological sequences in databases based on similarity.


aTrue

✓


bFalse

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ceither true and false

✖


dnone of the mentioned

✖


View Answer True

If one is looking for protein homologs encoded in newly sequenced genomes, one may use TBLASTN, which translates nucleotide database sequences in all six open reading frames.


aTrue

✓


bFalse

✖


ceither true and false

✖


dnone of the mentioned

✖


View Answer True

Which of the following is not correct about BLAST?


aThe BLAST web server has been designed in such away as to simplify the task of program selection

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bThe programs are organized based on the type of query sequences

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cThe programs are organized based on the type of nucleotide sequences, or nucleotide sequence to be translated

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dBLAST is not based on heuristic searching methods

✓



TBLASTX queries protein sequences to anucleotide sequence database with the sequences translated in all six reading frames.


aTrue

✖


bFalse

✓


ceither true and false

✖


dnone of the mentioned

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View Answer False

BLASTX uses protein sequences as queries to search against a protein sequence database.


aTrue

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bFalse

✓


ceither true and false

✖


dnone of the mentioned

✖


View Answer False

Which of the following is not a variant of BLAST?


aBLASTN

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bBLASTP

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cBLASTX

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dTBLASTNX

✓


View Answer TBLASTNX

A recent improvement in the implementation of BLAST is the ability to provide gapped alignment.


aTrue

✓


bFalse

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ceither true and false

✖


dnone of the mentioned

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View Answer True

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