Bioinformatics Mcqs

Page No. 23

Sensitivity refers to the ability to find as many correct hits as possible.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

Which of the following is not one of the requirements for implementing algorithms for sequence database searching?


aSize of the dataset


bSensitivity


cSpecificity


dSpeed


View Answer Size of the dataset

Dynamic programming method is the fastest and most practical method.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer False

The main application of pairwise alignment is retrieving biological sequences in databases based on similarity.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

If one is looking for protein homologs encoded in newly sequenced genomes, one may use TBLASTN, which translates nucleotide database sequences in all six open reading frames.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

Which of the following is not correct about BLAST?


aThe BLAST web server has been designed in such away as to simplify the task of program selection


bThe programs are organized based on the type of query sequences


cThe programs are organized based on the type of nucleotide sequences, or nucleotide sequence to be translated


dBLAST is not based on heuristic searching methods



TBLASTX queries protein sequences to anucleotide sequence database with the sequences translated in all six reading frames.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer False

BLASTX uses protein sequences as queries to search against a protein sequence database.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer False

Which of the following is not a variant of BLAST?


aBLASTN


bBLASTP


cBLASTX


dTBLASTNX


View Answer TBLASTNX

A recent improvement in the implementation of BLAST is the ability to provide gapped alignment.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

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