Bioinformatics Mcqs

Page No. 11

. A length and distance that gives the highest overall probability may then be determined. Such alignments are initially found using ________


aa particular scoring matrix only


ban alignment algorithm only


can alignment algorithm and a particular scoring matrix


ddot method



Another difficulty in Bayesian methods is deciding on the length of sequence that was duplicated.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

In Bayesian methods, difficulty with making estimations is that the estimate depends on the following Assumption. (Assumption – The mutation rate in sequences has been constant with time and that the rate of mutation of all nucleotides is the same.)


a True


bFalse


ceither true and false


dnone of these


View Answer True

In a type of probability, analysis is to calculate the odds score for one event OR a second event, or of a series of events. In this case, the odds scores are _______


a multiplied


b subtracted


cadded and multiplied


dadded


View Answer added

If the purpose is to calculate the probability of one event AND a second event, the odds scores for the events are _________


aadded


bmultiplied


cmultiplied and added


d subtracted


View Answer multiplied

With the application of Bayesian methods, the most probable repeat length and evolutionary time since the repeat was formed may be derived.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

By whom and when were the Bayesian methods applied first?


aSmith-Waterman, 1981


bAgarwal and States, 1996


cSmith-Waterman, 1996


dAgarwal and States, 1981



Sequence similarity and sequence identity are synonymous for nucleotide sequences and protein sequences as well.


aTrue


bFalse


ceither true and false


dnone of these


View Answer False

Shorter sequences require higher cutoffs for inferring homologous relationships than longer sequences.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

Sequence similarity can be quantified using ________ homology is a ______ statement.


apercentages, quantitative


bpercentages, qualitative


cratios, qualitative


d ratios, quantitative



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