Bioinformatics Mcqs

Page No. 11

. A length and distance that gives the highest overall probability may then be determined. Such alignments are initially found using ________


aa particular scoring matrix only

✖


ban alignment algorithm only

✖


can alignment algorithm and a particular scoring matrix

✓


ddot method

✖



Another difficulty in Bayesian methods is deciding on the length of sequence that was duplicated.


aTrue

✓


bFalse

✖


ceither true and false

✖


dnone of these

✖


View Answer True

In Bayesian methods, difficulty with making estimations is that the estimate depends on the following Assumption. (Assumption – The mutation rate in sequences has been constant with time and that the rate of mutation of all nucleotides is the same.)


a True

✓


bFalse

✖


ceither true and false

✖


dnone of these

✖


View Answer True

In a type of probability, analysis is to calculate the odds score for one event OR a second event, or of a series of events. In this case, the odds scores are _______


a multiplied

✖


b subtracted

✖


cadded and multiplied

✖


dadded

✓


View Answer added

If the purpose is to calculate the probability of one event AND a second event, the odds scores for the events are _________


aadded

✖


bmultiplied

✓


cmultiplied and added

✖


d subtracted

✖


View Answer multiplied

With the application of Bayesian methods, the most probable repeat length and evolutionary time since the repeat was formed may be derived.


aTrue

✓


bFalse

✖


ceither true and false

✖


dnone of these

✖


View Answer True

By whom and when were the Bayesian methods applied first?


aSmith-Waterman, 1981

✖


bAgarwal and States, 1996

✓


cSmith-Waterman, 1996

✖


dAgarwal and States, 1981

✖



Sequence similarity and sequence identity are synonymous for nucleotide sequences and protein sequences as well.


aTrue

✖


bFalse

✓


ceither true and false

✖


dnone of these

✖


View Answer False

Shorter sequences require higher cutoffs for inferring homologous relationships than longer sequences.


aTrue

✓


bFalse

✖


ceither true and false

✖


dnone of these

✖


View Answer True

Sequence similarity can be quantified using ________ homology is a ______ statement.


apercentages, quantitative

✖


bpercentages, qualitative

✓


cratios, qualitative

✖


d ratios, quantitative

✖



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