Bioinformatics Mcqs

Page No. 89

_______ of the Drosophila sequence is composed of TEs and _____ is heterochromatic regions that do not include genes.


a one-fourth, one-third


bone-fifth, one-fourth


cone-sixth, one-eighth


d one-sixth, one-third



In Metabolic pathways and regulation, as genes are identified in a new genome sequence, some will be found that are known to act sequentially in a metabolic pathway or to have a known role in gene regulation in other organisms.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

. In Protein 2D gel Electrophoresis, Individual proteins produced by the genome can be separated to _____ by this method and specific ones identified by various _______


a smaller extent, biochemical and immunological tests


b a large extent, biochemical and immunological tests


ca large extent, biochemical tests only


dsmaller extent, purely mechanical tests



In Proteolysis and fragment sequencing, Protein spots may be excised from a two-dimensional protein gel and subjected to a combination of amino acid sequencing and cleavage analyses using the techniques of mass spectrometry and high-pressure liquid chromatography.


a`True`


bFalse


ceither ture and false


dnone of these


View Answer True

WU-BLAST produces P scores and BLAST (NCBI) produces E scores where _________


aE = ln (1 + P2)


b E = ln (1 – P2)


c E = ln (1 + P)


d E = ln (1 – P)``


View Answer E = ln (1 – P)

In the program COGNITOR each protein in the proteome is used as a query of a database of protein clusters.


aTrue


bFalse


ceither ture and false


dnone of thses


View Answer True

New gene functions are thought to be gained by duplication of an existing gene creating two tandem copies.


a True


bFalse


ceither ture and false


dnone of thses


View Answer True

Pseudogenes are DNA sequences that were derived from distinct genes but which have acquired mutations that are deleterious to function in the same period of time.


a True


b False


ceither ture and false


dnone of these


View Answer False

Processed pseudogenes are also derived from a functional gene and they contain introns and a promoter.


aTrue


bFalse


ceither ture and false


dnone of these


View Answer False

In all-against-all self comparison, A comparison is made in which every protein is used as a query in a similarity search against a database composed of the rest of the proteome, and the significant matches are identified by a low expect value.


a True


bFalse


ceither ture and fales


dnone of these


View Answer True

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