Bioinformatics Mcqs

Page No. 88

Gene identification in prokaryotic organisms is simplified by their lacking _________


a exons


b introns


ccoding segments


d useful nucleotide sequences


View Answer introns

TEs (Transposable Elements) can at most comprise one-fourth of the genome sequence.


aTrue


bFalse


ceither ture and false


done of these


View Answer False

In case of genome sequence assembly which of the given statement is incorrect?


aFull chromosomal sequences are assembled from the overlaps in a highly redundant set of fragments by an automatic computational method or from the fragment order on a physical map


b Chromosome cloning is carried out in bacterial artifical chromosomes (BACs)


chromosomes of a target organism are purified, fragmented, and subcloned in fragments of size hundreds of bp


dGenome sequences are assembled from DNA sequence fragments of approximate length 500 bp obtained using DNA sequencing machines



Screening the predicted protein sequences against ______ library confirms the prediction and expression of the gene.


aexpressed sequence tag (EST)


btags


cpalindromes


dproteomes



Each genome sequence is scanned for protein-encoding genes using gene models trained on known gene sequences from the same organism.


a True


bFalse


ceither ture and false


dnone of these


View Answer True

. Sequencing of genomes depends on the assembly of a large number of DNA reads into a linear, contiguous DNA sequence.


aTrue


bFalse


ceither ture and false


dnone of these


View Answer True

The higher the E value, the more significant the alignment between a pair of matching sequences.


aTrue


bFalse


ceither ture and false


dnone of these


View Answer False

Which of the given statement is incorrect?


aAs in an all-by-all protein comparison within a proteome, a matrix of alignment scores with E values is made, and the most closely related sequences in the two organisms are identified


bTo perform a between-proteome analysis, proteome databases are made for the known and predicted genes of two or more genomes


cEach protein of one proteome is selected in turn as a query of the proteome of another organism or the combined proteome of a group of organisms


dEach protein of one proteome is selected in turn as a query of the proteome of another single organism only



The ________ are _______ by genetic structure to retroviruses.


a STR retrotransposons, related


bLTR retrotransposons, related


cSTR transposons, related


dLTR retrotransposons, not related



Yeast is about ______ compact than E. coli.


a fivefold, less


b threefold, more


ctwofold, less


dtwofold, more


View Answer twofold, less

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