Bioinformatics Mcqs

Page No. 88

Gene identification in prokaryotic organisms is simplified by their lacking _________


a exons

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b introns

✓


ccoding segments

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d useful nucleotide sequences

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View Answer introns

TEs (Transposable Elements) can at most comprise one-fourth of the genome sequence.


aTrue

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bFalse

✓


ceither ture and false

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done of these

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View Answer False

In case of genome sequence assembly which of the given statement is incorrect?


aFull chromosomal sequences are assembled from the overlaps in a highly redundant set of fragments by an automatic computational method or from the fragment order on a physical map

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b Chromosome cloning is carried out in bacterial artifical chromosomes (BACs)

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chromosomes of a target organism are purified, fragmented, and subcloned in fragments of size hundreds of bp

✓


dGenome sequences are assembled from DNA sequence fragments of approximate length 500 bp obtained using DNA sequencing machines

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Screening the predicted protein sequences against ______ library confirms the prediction and expression of the gene.


aexpressed sequence tag (EST)

✓


btags

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cpalindromes

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dproteomes

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Each genome sequence is scanned for protein-encoding genes using gene models trained on known gene sequences from the same organism.


a True

✓


bFalse

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ceither ture and false

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dnone of these

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View Answer True

. Sequencing of genomes depends on the assembly of a large number of DNA reads into a linear, contiguous DNA sequence.


aTrue

✓


bFalse

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ceither ture and false

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dnone of these

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View Answer True

The higher the E value, the more significant the alignment between a pair of matching sequences.


aTrue

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bFalse

✓


ceither ture and false

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dnone of these

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View Answer False

Which of the given statement is incorrect?


aAs in an all-by-all protein comparison within a proteome, a matrix of alignment scores with E values is made, and the most closely related sequences in the two organisms are identified

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bTo perform a between-proteome analysis, proteome databases are made for the known and predicted genes of two or more genomes

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cEach protein of one proteome is selected in turn as a query of the proteome of another organism or the combined proteome of a group of organisms

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dEach protein of one proteome is selected in turn as a query of the proteome of another single organism only

✓



The ________ are _______ by genetic structure to retroviruses.


a STR retrotransposons, related

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bLTR retrotransposons, related

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cSTR transposons, related

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dLTR retrotransposons, not related

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Yeast is about ______ compact than E. coli.


a fivefold, less

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b threefold, more

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ctwofold, less

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dtwofold, more

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View Answer twofold, less

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