Bioinformatics Mcqs

Page No. 87

Which of the given features is incorrect?


aTEs are present in few particular chromosomes


bTEs are present in all of the chromosomes


c Abundance of TEs varies


d TEs can comprise a large portion of the genomes of higher eukaryotes, both plants and animals



A third category of TEs has features of both class I and class II TEs. These miniature, inverted repeat TEs (MITES) are ________ in length.


a400 bp


b500 Mbp


c300 kbp


d 600 kbp


View Answer 400 bp

The human genome contains about _________ of class II of elements that probably predate human evolution (Smit 1996).


a2,000 copies


b 200,000 copies


c2,00,00,000 copies


d20,00,000 copies


View Answer 200,000 copies

Vertebrate chromosomes have long (>300 kb) regions of distinct GC richness, repeat content, and gene density, designated isochores in a model of genome organization proposing that genomes are made up of distinct segments of unique composition.


aTrue


bFalse


ceither ture and false


dnone of these


View Answer True

_____ of the human genome comprises one particular family of the SINE Element, designated Alu (1.2 million copies).


a10%


b 20%


c 60%


d40%


View Answer 10%

The retroposons include short _________ interspersed nuclear elements (SINES).


a90–4000 bp long


b80–500 Mbp long


c80–300 bp long


d 100–3000 bp long


View Answer 80–300 bp long

More than _____ of the human genome consists of interspersed repetitive sequences derived from TEs (transposable elements).


aone-third


bone-eighth


cone-fifth


dhalf


View Answer one-third

Which of the given statement is incorrect about the gene map?


aGene order in two related organisms reflects the order that was present in a common ancestor genome. Chromosomal breaks followed by reassembly of fragments in a different order can produce new gene maps


b Gene order is only revealed by the physical order of genes on the chromosome


cSequence variations (polymorphisms) that are close to (tightly linked) a trait may be used to trace the trait by virtue of the fact that the polymorphism and the trait are seldom separated from one generation to the next


dThese types of evolutionary changes in genomes have been modeled by computational methods



Which of the given statement is incorrect about Functional Genomics?


aFunctional genomics involves the preparation of mutant or transgenic organisms with a mutant form of a particular gene usually designed to prevent expression of the gene


b An abnormal properties of the mutant organism does not reveal the gene function


cWhen two or more members of a gene family are found, rather than a single match to a known gene, the biological activity of these members may be analyzed by functional genomics to look for diversification of function in the family


dA more detailed analysis of the relative amount of sequence variability in a chromosomal region within populations of closely related species can reveal the presence of genes that are under selection



Which of the following information is not directly obtained by microarray analysis?


a Which genes are expressed at a particular stage of the cell cycle


bWhich genes are expressed at a particular stage of developmental cycle of an organism


cWhich genes are depleted at what time


dGenes that respond to a given environmental signal to the same extent



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