Bioinformatics Mcqs

Page No. 72

McPromoter, a web-based program, uses a neural network to make promoter predictions.


a True


b False


ceither true and false


dnone of these


View Answer True

Which of the following is incorrect regarding First EF?


a It is a program that predicts promoters for bacterial DNA


bIt is a web-based program that predicts promoters for human DNA


cIt stands for First Exon Finder


d It integrates gene prediction with promoter prediction



Which of the following is incorrect regarding Cluster-Buster?


aIt is an HMM-based web-based program


b A query sequence is scanned with a window size of 1 kb for putative regulatory motifs using motif HMMs


c It works by detecting a region of high concentration of unknown transcription factor binding sites and regulatory motifs at the initiation


dIt is designed to find clusters of regulatory binding sites



Which of the following is incorrect regarding Eponine?


a It is a web-based program that predicts transcription start sites


b It is a web-based program that particularly predicts tranpososons and retropososons


cThe regulatory sites include the TATA box, the CCAAT box, and CpG islands


d It is based on a series of pre-constructed PSSMs of several regulatory sites



CpGProD is a web-based program that predicts promoters containing a high density of CpG islands _______


a in archea genomic sequences


b in mammalian genomic sequences


cin eukaryotic and bacterial genomic sequences


donly in bacterial genomic sequences



The eukaryotic transcription initiation is less dependent on transcription factors.


a True


bFalse


ceither true and false


dnone of these


View Answer False

Which of the following is untrue about PhyloCon?


aIt stands for Phylogenetic Consensus


bIt is used to identify regulatory motifs


c It is a UNIX program that combines phylogenetic footprinting with gene expression profiling analysis


dNo conservation among orthologous genes and conservation among coregulated genes is a disadvantage



INCLUSive is a suite of web based tools designed to streamline the process of microarray data collection and sequence motif detection.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

Which of the following is untrue about Expression Profiling–Based Method?


aGenes with similar expression profiles are considered coexpressed, which can be identified through a clustering approach


bThis approach appears to be less effective for finding transcription factor binding sites


cAn advanced alignment-independent profile construction method such as EM and Gibbs motif sampling is often used in finding the subtle sequence motifs


dThe basis for coexpression is thought to be due to common promoters and regulatory elements



Which of the following is untrue about FootPrinter?


a It is a web-based program for phylogenetic footprinting using multiple input sequences


bThe motifs from organisms spanning over the widest evolutionary distances are identified as promoter or regulatory motifs


c The program performs multiple alignment of the input sequences to identify conserved motifs


dThe user does not necessarily provides a phylogenetic tree that defines the evolutionary relationship of the input sequences



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