Bioinformatics Mcqs

Page No. 70

In addition to the RNA polymerase, there are also a number of DNA-binding proteins that facilitate the process of transcription.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

The promoter sequence may determine the expression of one gene or a number of linked genes downstream.


aTrue


bFalse


ceither ture and false


dnone of the mentioned


View Answer True

The upstream sequence where the σ protein binds constitutes the promoter sequence.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

n bacteria, transcription is initiated by DNA polymerase.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer False

To increase the specificity of prediction, a unique feature of eukaryotic promoter is employed, which is the presence of CpG islands.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

Which of the following is incorrect regarding the Prediction for Eukaryotes?


aThe consensus patterns are only derived from bioinformatics studies


bThe experimentally determined DNA binding sites are compiled into profiles and stored in a database for scanning an unknown sequence to find similar conserved patterns


cThe consensus patterns are derived from experimentally determined DNA binding sites


dThe ab initio method for predicting eukaryotic promoters and regulatory elements relies on searching the input sequences for matching of consensus patterns of known promoters and regulatory elements



Which of the following is incorrect regarding FindTerm?


aIt is a program for searching bacterial ρ-independent termination signals located at the end of operons


bIt is a program for searching bacterial ρ-dependent termination signals located within the operons


cThe predictions are made based on matching of known profiles of the termination signals combined with energy calculations


d It is available from the same site as FGENES and BPROM



In BPROM, once the operons are assigned, the program is able to predict putative promoter sequences.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

Which of the following is incorrect regarding BPROM?


aIt is a web-based program for prediction of bacterial promoters


bIt is a web-based program only for prediction of eukarotic promoters


cIt uses a linear discriminant function


dThe linear discriminant function is combined with signal and content information



Which of the following is correct regarding the method for prokaryotic operon prediction?


aIt relies on two kinds of information: gene orientation and intergenic distances of


b It relies only on the gene orientation and intergenic distances of a pair of genes of interest


c It relies only on the conserved linkage of the genes based on comparative genomic analysis


dThe prediction cannot be done manually using the rules



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