Bioinformatics Mcqs

Page No. 62

Which of the following is incorrect about Bootstrapping?


aIt is a statistical technique that tests the sampling errors of a phylogenetic tree


bIt does the tests by repeatedly sampling trees through slightly perturbed datasets


cA newly constructed tree is not biased at all


dThe robustness of the original tree can be assessed here



MrBayes has a range of probabilistic models available to search for a set of trees with the lowest posterior probability.


a True


bFalse


ceither true and false


dnone of these


View Answer False

MrBayes is a Bayesian phylogenetic inference program.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

In PHYML, The tree searching _____ when the total ML score no longer ______


aceases, increases


bstops, decreases


cterminates, decreases


dstops, increases


View Answer stops, increases

PHYML is a web-based _______ program using the _____


a phylogenetic, GA (Genetic Algorithm)


bsequence based alignment, GA (Genetic Algorithm)


cphylogenetic, dynamic programming


dsequence based alignment, dynamic programming



Which of the following is untrue regarding TREE-PUZZLE?


aIt is a program performing quartet puzzling


bIt allows various substitution models for likelihood score estimation


cIt doesn’t incorporate a discrete γ model


d Because of the heuristic nature of the program, it allows ML analyses of large datasets



In PAUP, to complete an analysis the user is not required to move between different subprograms while keeping modifying names of the intermediate output files.


aTrue


b False


ceither true and false


dnone of these


View Answer True

Phylip stands for Phylogenetic inference package (by Joe Felsenstein).


aTrue


b False


ceither true and false


dnone of these


View Answer True

In PAUP, The distance options include NJ, ME, FM, and UPGMA.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

PAUP is a Macintosh program (UNIX version available in the GCG package) with a very user-friendly graphical interface.


a True


bFalse


ceither true and false


dnone of these


View Answer True

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