Bioinformatics Mcqs

Page No. 58

A gene phylogeny only describes the evolution of a particular gene or encoded protein.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

In Jukes–Cantor Model to correct evolutionary distances, A formula for deriving evolutionary distances that include hidden changes is introduced by using a logarithmic function. It is ____


a dAB = −(3/4) log[1 − (4/7)pAB]


bdAB = −(3/4) ln[1 − (5/3)pAB]


cdAB = −(3/4) log[1 − (4/3)pAB]


ddAB = −(3/4) ln[1 − (4/3)pAB]



DNA sequences are sometimes more biased than protein sequences because of preferential codon usage in different organisms.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

Protein sequences can remain the same while the corresponding DNA sequences have more room for variation.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

In many cases ______ sequences are preferable to ______ sequences because they are relatively ____ conserved.


aprotein, nucleotide, less


bnucleotide, protein, less


cprotein, nucleotide, more


dnucleotide, protein, more



For studying the evolution of ________ divergent groups of organisms, one may choose either ______ nucleotide sequences, such as ribosomal RNA or protein sequences.


aless widely, slowly evolving


bmore widely, slowly evolving


cmore widely, rapidly evolving


dless widely, rapidly evolving



Which of the following is incorrect statement about Molecular Markers?


aFor studying very closely related organisms, protein sequences are preferred


b The decision to use nucleotide or protein sequences depends on the purposes of the study


cFor constructing molecular phylogenetic trees, one can use either nucleotide or protein sequence data


d The decision to use nucleotide or protein sequences depends on the properties of the sequences



It can be computationally very demanding to find a true phylogenetic tree when the number of sequences is large.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

For unrooted trees, the number of unrooted tree topologies (NU) is ________


a NU = (2n− 5)!/2n−3(n− 5)!


bNU = (2n− 5)!/2n−3(n− 3)!


cNU = (2n− 5)!/2−2(n− 3)!


d NU = (2n− 5)!/2n(n− 3)!



The number of rooted trees (NR) for n taxa is ______


aNR = (2n− 3)!/2n+2 (n− 2)!


bNR = (2n− 3)!/2n (n− 2)!


cNR = (2n− 3)!/2n−2 (n− 5)!


dNR = (2n− 3)!/2n−2 (n− 2)!



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