Bioinformatics Mcqs

Page No. 56

The justification behind Rosetta stone method is that when two domains are fused in a single protein, they have to be in _______ proximity to perform a common function.


adistant


bclose


cextremely distant


dextremely close


View Answer extremely close

Which of the following is untrue regarding the Predicting Interactions Based on Domain Fusion?


a It is based on gene fusion events


bPredicting protein–protein interactions is called the “Rosetta stone” method


cA fused protein often reveals relationships between its domain components


dA fused protein doesn’t necessarily reveal about the relationships between its domain components



. An alternative approach to determining protein–protein interactions is to use a large-scale affinity purification technique that involves attaching fusion tags to proteins and purifying the associated protein complexes in an affinity chromatography column.


a True


b False


ceither true and false


dnone of these


View Answer True

If the bait and prey proteins _______ they bring the DNA-binding and trans-activation domains in such close proximity that they reconstitute the function of the transcription activator, turning ____ the expression of a reporter gene as a result. Which of the following is not the correct pair of blanks?


aphysically interact, on


bdo not interact, on


cdo not interact, off


d stop interacting, off


View Answer do not interact, on

Which of the following is untrue regarding the classic yeast two-hybrid method?


at is used for the detection of Protein interactions


bMethod that relies on the interaction of “bait” and “prey” proteins in molecular constructs in yeast


cDNA-binding domain and a trans-activation domain don’t necessarily interact


dIn this strategy, a two-domain transcriptional activator is employed as a helper for determining protein–protein interactions



Molecular clock is an assumption by which molecular sequences evolve at varying rates.


aTrue


bFalse


ceither true and false


dnone of these


View Answer False

Because there is no indication of which node represents an ancestor, there is no direction of an evolutionary path in an unrooted tree.


a True


b False


ceither true and false


dnone of these


View Answer True

Which of the following is incorrect regarding the terminologies of phylogenetics?


aThe connecting point where two adjacent branches join is called a node


bNode represents an inferred ancestor of extant taxa


cAt the tips of the branchAt the tips of the branches are long lost species or sequenceses are long lost species or sequences


d The lines in the tree are called branches



Building phylogenetic tree involves bifurcation and multifurcation.


a True


bFalse


ceither true and false


dnone of these


View Answer True

To use molecular data to reconstruct evolutionary history requires making a number of reasonable assumptions. Which of the following is incorrect about it?


aThe molecular sequences used in phylogenetic construction are homologous


b The molecular sequences used in phylogenetic construction share a common origin


cPhylogenetic divergence cannot be bifurcating


dParent branch splits into two daughter branches at any given point



Goto Page No.

Page 56 of 92

Alphabetical MCQs Categories

Here below You find all kind of categories of MCQs in alphabetical order.


"Comprehensive Collection of MCQs: Alphabetically Organized by Subject"

"Discover an extensive collection of multiple-choice questions (MCQs) neatly categorized by subject from A to Z. This resource is designed for anyone eager to explore various topics in a straightforward and organized manner. Whether you're a student preparing for exams, an educator seeking supplementary materials, or simply curious about different subjects, this compilation offers a convenient way to learn and assess your knowledge. With questions arranged alphabetically, navigation is effortless, allowing you to delve into subjects of interest at your own pace. Engage, learn, and expand your understanding with this accessible and comprehensive repository of MCQs!"


BolPakistan

bolpakistan.com.pk includes Job Mcqs and Pak Mcqs is the Top Largest Mcqs Forum in World, in which you can read Mcqs of All Subjects, PPSC test preparation, FPSC, NTS and PPSC PAST PAPERS, PPSC PAST MCQS. A Collection of Repeated MCQs for JOBs seekers.

Copyright © 2024, Designed & Developed by BolPakistan