Bioinformatics Mcqs

Page No. 39

The dynamic programming method produces ____ structure with _____ score.


a one, single best


bmultiple, single best


cmultiple, multiple


d single, multiple


View Answer one, single best

In dynamic programming, in ab initio methods, Often ________ base pairing and energy terms of the base pairing _____ incorporated into the scoring process.


aG-C, are


bG–U, are not


cG–U, are also


dG-C, are not


View Answer G–U, are also

In ab initio methods, a quantitative approach such as dynamic programming can be used to assemble a final structure with optimal base-paired regions.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

In dynamic programming, in ab initio methods, the use of a dot plot can be effective in finding a ____ secondary structure in a ________ molecule.


a multiple, large


bsingle, large


csingle, small


dmultiple, small


View Answer single, small

In dot matrix in ab initio methods, one way to reduce the noise in the matrix is to select an appropriate window size of a maximum number of contiguous base matches.


aTrue


b False


ceither true and false


dnone of these


View Answer False

In dot matrix in ab initio methods, the diagonals _____________ to the main diagonal represent regions that can self hybridize.


aparallel


bcutting in random fashion


cperpendicular


dadjacent parallel


View Answer perpendicular

Which of the following is true about the RNAalifold?


aDynamic programming is not involved


bMinimum free energy method is not used


cOnly minimum free energy is used


dCovariation information is taken into consideration



The predefined alignment requiring method also depends on the quality of the input alignment. If there ___ errors in the alignment, covariation signals ____ detected.


a are, will be


b are, will not be


c are not, will not be


dare not, possibly will not be


View Answer are, will not be

The type of algorithm that _____ predefined alignment is ______ for reasonably conserved sequences.


adoesn’t require, more successful


brequires, less successful


cdoesn’t require, relatively successful


d requires, relatively successful



The type of algorithm that requires predefined alignment, requires the user to provide _______ alignment as input.


anot necessarily an alignment


b multiple only


cpairwise or multiple


dpair wise only


View Answer pairwise or multiple

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