Bioinformatics Mcqs

Page No. 42

The Second assumption in predicting RNA secondary structure is that the energy associated with any position in the structure is _____ influenced by local sequence and structure.


aonly


b not at all


cpartially


dnever


View Answer only

In predicting RNA secondary structure, some simplifying assumptions are usually made, like the _____ structure is similar to the _____


a most likely, energetically most unstable structure


bmost unlikely, energetically most stable structure


c most likely, energetically most stable structure


d least likely, energetically most stable structure



____ wobble pairs may be produced in these double-stranded regions.


aA/A


b A/U


c G/C


dG/U


View Answer G/U

RNA secondary structure is composed primarily of triple-stranded RNA regions formed by folding the single-stranded molecule back twice on itself.


aTrue


bFalse


ceither true and false


dnone of these


View Answer False

A type of RNA secondary structure prediction method takes into account conserved patterns of base-pairing that are conserved during evolution of a given class of RNA molecules.


a True


b False


ceither true and false


dnone of these


View Answer True

Which of the following is incorrect about the RNA structure prediction?


aGiven the sequence, it provides an ab initio prediction of secondary structure


bFrom the many possible choices of complementary sequences that can potentially base-pair, the compatible sets that provide the highest energy molecules are chosen


c Structures with energies almost as stable as the most stable one may also be produced


dRegions whose predictions are the most reliable can be identified from such an analysis



The application of SCFGs to RNA secondary structure analysis is very similar in form to the probabilistic covariance models.


aTrue


bFalse


ceither true and false


dnone of these


View Answer True

In a SCFG, each production of a non-terminal symbol has an associated probability for giving rise to the resulting product, and there are a set of productions, each giving a different result.


aTrue


b False


ceither true and false


dnone of these


View Answer True

The use of SCFGs in RNA secondary structure production analysis is in fact very similar to that of the covariance model, with the grammatical productions resembling the nodes in the ordered binary tree.


a True


b False


ceither true and false


dnone of these


View Answer True

______ regions in sequences, such as those in RNA that will form secondary structures, are an example of such context-free sequences.


anon-interlocking


bnon-Complementary


c complementary


d non-compatible


View Answer complementary

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