Bioinformatics Mcqs

Page No. 27

Par Align is a web-based server that uses parallel processors to perform exhaustive sequence comparisons using either a parallelized version of the Smith–Waterman algorithm or a heuristic program for further speed gains.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

Scan PS is a web-based program that implements a modified version of the Needleman-Wunsch algorithm.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer False

FASTA and BLAST are __________ but __________ for larger datasets.


afaster, more sensitive


bfaster, less sensitive


cslower, less sensitive


dslower, more sensitive



The rigorous dynamic programming method is normally not used for database searching because it is slow and computationally expensive.


aTrue


bFalse


ceither true and false


dnone of the mentioned


View Answer True

Which of the following is not correct about the NMR?


aIt stands for Nuclear Magnetic Resonance


bNMR spectroscopy detects spinning patterns of atomic nuclei in a electric field


cNMR spectroscopy detects spinning patterns of atomic nuclei in a magnetic field


dProtein samples are labeled with radioisotopes such as 13C and 15N



Which of the following is not correct about the X-ray Crystallography?


a In x-ray protein crystallography, proteins need to be grown into large crystals in which their positions are fixed in a repeated, ordered fashion


bThe protein crystals are illuminated with an intense x-ray beam


cThe x-rays are deflected by the electron clouds surrounding the atoms in the crystal producing a regular pattern of diffraction


dThe protein crystals are illuminated with an intense infrared beam



Which of the following is not correct about the Integral Membrane Proteins?


aMembrane proteins exist in lipid bilayers of cell membranes


bThe exterior of the proteins spanning the membrane must be very hydrophobic to be stable


cThe exterior of the proteins spanning the membrane must be very hydrophilic to be stable


dMost typical transmembrane segments are α-helices



Which of the following is not correct about the Coils and Loops?


aThey are regular structures


bThey are irregular structures


cThe loops are often characterized by sharp turns or hairpin-like structures


dIf the connecting regions are completely irregular, they belong to random coils



Which of the following is not correct about the β-sheet?


aA β-sheet is a fully extended configuration built up from several spatially adjacent regions of a polypeptide chain


bEach region involved in forming the β-sheet is a β-strand


cThe β-strand conformation is pleated with main chain backbone zigzagging and side chains positioned on same sides of the sheet


dβ-Strands are stabilized by hydrogen bonds between residues of adjacent strands



Which of the following is not correct about the α-Helices?


aAn α-helix has a main chain backbone conformation that resembles a corkscrew


bNearly all known α-helices are right handed, exhibiting a leftward spiral form


cNearly all known α-helices are right handed, exhibiting a rightward spiral form


dIn right handed helix, there are 3.6 amino acids per helical turn



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