Pharmacology MCQs

Page No. 31

Which drugs had high first pass effect_____________?


a Amiodarone


b Phenytoin


cVerapamil


dDisorpyamide


View Answer Verapamil

Combination of ampicillin and gentamicin is an example of_____________?


a Indifference


bSynergy


cAntagonism


dBacterial symbiosis


View Answer Synergy

All of the following statements regarding biovailability of a drug are true except______________?


a It is the proportion (fraction) of unchanged drug that reaches the systemic circulation


bBiovailability of an orally administered drug can be calculated by comparing the area under cure (o-a) after oral and intravenous (IV) administration


c Low oral biovailability always and necessarily mean poor absorption


dBiovailability can be determined from plasma concentration or urinary excretion data



Drug efficacy refers to_________________?


aRange of disease in which the drug beneficial


bMaximal intensity of response that can be produced by the drug


cThe therapeutic does range of the drug


dThe therapeutic index of the drug



Intramuscular route is precluded during the medication of________________?


aAnti-hypertensives


bAnti-diabetics


cAnticoagulants


dAnti-fibrinolytics


View Answer Anticoagulants

For Arsenic poisoning Antidote is_____________?


aPenicillamine


bE.D.T.A


cDesferrixamine


d B.A.L


View Answer B.A.L

All the following increases drug metabolism by activating cytochrome enzyme, EXCEPT___________?


aTetracycline


bCimetidine


cRifampicin


dPhenobarbitone


View Answer Cimetidine

Loading dose depends on_____________?


aVolume of distribution


bClearance


c Rate of administration


dHalf life



Drugs exhibiting first pass metabolism are all EXCEPT one______________?


aMorphine


bNitroglycerine


cPropranolol


dSalicylates


View Answer Salicylates

When a drug creates an effect that is unpredictable and unique it is termed as____________?


aSide effect


bToxicity effect


c Idiosyncratic effect


dDrug on Drug effect



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