Pharmacology MCQs

Page No. 31

Which drugs had high first pass effect_____________?


a Amiodarone

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b Phenytoin

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cVerapamil

✓


dDisorpyamide

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View Answer Verapamil

Combination of ampicillin and gentamicin is an example of_____________?


a Indifference

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bSynergy

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cAntagonism

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dBacterial symbiosis

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View Answer Synergy

All of the following statements regarding biovailability of a drug are true except______________?


a It is the proportion (fraction) of unchanged drug that reaches the systemic circulation

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bBiovailability of an orally administered drug can be calculated by comparing the area under cure (o-a) after oral and intravenous (IV) administration

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c Low oral biovailability always and necessarily mean poor absorption

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dBiovailability can be determined from plasma concentration or urinary excretion data

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Drug efficacy refers to_________________?


aRange of disease in which the drug beneficial

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bMaximal intensity of response that can be produced by the drug

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cThe therapeutic does range of the drug

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dThe therapeutic index of the drug

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Intramuscular route is precluded during the medication of________________?


aAnti-hypertensives

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bAnti-diabetics

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cAnticoagulants

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dAnti-fibrinolytics

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View Answer Anticoagulants

For Arsenic poisoning Antidote is_____________?


aPenicillamine

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bE.D.T.A

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cDesferrixamine

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d B.A.L

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View Answer B.A.L

All the following increases drug metabolism by activating cytochrome enzyme, EXCEPT___________?


aTetracycline

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bCimetidine

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cRifampicin

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dPhenobarbitone

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View Answer Cimetidine

Loading dose depends on_____________?


aVolume of distribution

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bClearance

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c Rate of administration

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dHalf life

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Drugs exhibiting first pass metabolism are all EXCEPT one______________?


aMorphine

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bNitroglycerine

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cPropranolol

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dSalicylates

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View Answer Salicylates

When a drug creates an effect that is unpredictable and unique it is termed as____________?


aSide effect

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bToxicity effect

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c Idiosyncratic effect

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dDrug on Drug effect

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