Pharmacology MCQs

Page No. 30

The phase I reactions of drug metabolism include The following except_____________?


a Hydolysis

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bReduction

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cOxidation

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dConjugation

✓


View Answer Conjugation

Secretory immunoglobulin is_____________?


a IgG

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bIgA

✓


cIgM

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dIgE

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View Answer IgA

Hepatic first pass metabolism is important in____________?


aDrugs given IM

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b Drugs taken orally

✓


cDrugs given IV

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dNone of the above

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View Answer Drugs taken orally

When allergic manifestations occur pursuant to use of antimicrobial agents, what of the following is seen____________?


aSkin eruptions

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bAngioneurotic edema

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cSerum imbalance

✖


dBoth A & B

✓


View Answer Both A & B

Allergic reactions depends on all except____________?


aprevious exposure to the drug

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bDosage of the drug received

✓


cPharmacological action of the drug

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dAntigen antibody reaction

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Therapeutic index is____________?


aLD 100/Ed100

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bED 100/LD 100

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cLD 50/ED500

✓


dED50/LD50

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View Answer LD 50/ED500

Drugs showing zero order kinetics of elimination_____________?


aAre more common than first order kinetics

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bDecrease in concentration exponentially with time

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cHave a half – life independent of dose

✓


dShow a plot of drug concentration versus time that is linear

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Zero order kinetics is seen with_______________?


aPhenytoin

✓


bPhenabarbtion

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cErythromycin

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dDigoxin

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View Answer Phenytoin

Idiosyncracy is known as to have_____________?


aGenetic component

✓


bPsychological component

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c Psysiological component

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dNutritional component

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View Answer Genetic component

Neuro adaptation to drug is same as______________?


aPhysical dependence

✓


bPsychological dependence

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cAddiction

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dHabituation

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View Answer Physical dependence

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